1*Risabh Kumar Pandey, 2Dr. Prashant Kumar Singh, 3Srishti Yadav, 4Aadhya Dubey
A B S T R A C T
Phytosome is produced by the reaction of mostly in stoichiometric amounts of phospholipid
standardized herbal phosphatidylcholine in an aprotic extract. The aim of the present review
was based on the properties, preparation methods and applications of Phytosomes. The
composition of phytosomes is complicated and includes both natural phytoconstituents and
phospholipids, such as the phosphatidylcholine-rich phospholipids found in soy. These
complexes are produced when phospholipids in stoichiometric proportions react with
phytoconstituents in an aprotic solvent. They increase bioavailability due to phospholipid
complex, thus improve therapeutic effect. They are required in fewer doses due to high
bioavailability. Because of their superior pharmacokinetic and pharmacological properties,
phytosomes can be used to treat liver issues resulting from either infection or metabolism.
Additionally, they possess UV, lipolytic, vasokinetic, anti-oedema, cicatrising, trophodermic,
nutraceutical, antioxidant, cardioprotective, and anti-wrinkle qualities. New formulations
known as phytosomes contain hydrophilic flavonoids and other related chemicals with enhanced
skin or gastrointestinal tract bioavailability. They offer several distinct advantages over other
conventional formulations. Phytosome production is a simple technique that might be swiftly
scaled up for commercial use.
Keywords: Phytosome, soya lecithin, phospholipids, topical drug delivery system.