A B S T R A C T
With many highly advanced devices available on the market, controlled release medication delivery systems have drawn a lot of interest in the last 20 years. The current study was based on the preparation, advantages and pharmaceutical application of controlled drug delivery system. The majority of oral controlled release systems rely on dissolution, diffusion, or a combination of both mechanisms to generate slow release of drug to the gastrointestinal milieu. Sustained release oral products employing dissolution as the rate-limiting step are in principle the simplest to prepare. In swelling-controlled drug delivery systems, the drug is dispersed or dissolved in the hydrophilic polymer when in a glassy (hard and rigid) state. In an aqueous solution, water penetrates the matrix and the glass transition temperature of the polymer is lowered below ambient temperature. Osmotic pressure is the driving factor that produces continuous medication release in these kinds of drug delivery systems. A semi-permeable membrane is applied around an osmotically active drug core or an osmotically inert drug core combined with an osmotically active salt to create this system. Controlled drug delivery systems in the pharmaceutical industry refer to technologies that allow for precise control over the rate, time, and place of drug release within the body. In conclusion, the field of controlledrelease technology is still being developed despite the numerous controlled-release appliances that have been studied and/or used recently. Significant improvements in medication research, together with improved and earlier preventive medicine diagnostics, have contributed to an increase in human life expectancy.
Keywords: Pharmaceutical application, controlled drug delivery system, merits, preparation techniques.